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The concomitant usage of DEMEROL Tablets or Oral Alternative and CYP3A4 or CYP2B6 inducers can reduce the plasma focus of meperidine [see Medical Pharmacology (twelve.three)], causing decreased efficacy or onset of a withdrawal syndrome in sufferers who've developed Bodily dependence to meperidine [see Warnings and Precautions (5.Vital: When T
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